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Bacteriostatic water does not neutralize or remove endotoxins

After one-third of the study participants have been enrolled and completed follow-up, the DSMBs will review the data and make recommendations concerning continuation, modification or termination of the study due to unexpectedly large beneficial effects or serious side effects and can suggest extension of the trial should the primary outcomes occur less often than anticipated

Choose based on your primary goal, start conservatively, and adjust based on results

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Rodent healing differs from human healing in various ways, and dose extrapolation involves assumptions that may not hold perfectly