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Ji H et al
That last point deserves attention
If not improving, contact your healthcare provider about potential dose adjustment or extended hold at current level
Week 1-2 (or 1-4): Start at 200-250mcg nightly
In a systematic review of weight loss and imaging outcomes in overweight or obese individuals with hip or knee OA, Daugaard and colleagues concluded that there was no consistent evidence that weight loss altered structural OA pathology, while also emphasizing major heterogeneity in the structural endpoints used across studies (Daugaard et al., 2020)
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