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Some biomarkers are usually increased relatively quickly after pollution treatment like: pH, lactic acid content , sebum production and secretion, advanced glycation end products (AGE), malondialdehyde (MDA) and squalene monohydroperoxide (SQOOH) (marker for lipid peroxidation), protein oxidation, cellular oxidative stress levels (radicals), Interleukin-1a (IL), IL-6
This is critical, as GSH is essential for T cell effector functions through its regulation of metabolic activity (Mak et al., 2017)
Depot Release for Chronic Conditions: For conditions like melasma or chronic photo-damage, a spike in antioxidant levels is less effective than steady levels
This complexity provides various physiological advantages, such as molecular messaging, cellular specificity, and response amplification
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