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Management: Management of long-term side effects involves monitoring and assessing the patients condition

Tirzepatide (Mounjaro/Zepbound) Tirzepatide is a dual GIP/GLP-1 receptor agonist that produces even greater weight loss than Semaglutide (average 20-22% of body weight)

Notably, WAT from obese individuals, both in human and mice studies, contained a higher number of mast cells, macrophages, and lymphocytes compared to the lean groups

GLP-1RA (geniposide) might be a potential therapeutic agent for GIOP ( Effects of Glucagon-Like Peptide-1 Receptor Agonists on Postmenopausal Osteoporosis In one study, liraglutide was used to treat streptozotocin (STZ)-induced diabetes and/or bilateral ovariectomy (OVX) rats for 8 weeks