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In addition, acylation with a fatty acid can also alter the distribution of drugs in the body and facilitate the development of oral formulations for peptide drugs [4]
They also highlight a recurring pattern in peptide drug development: early safety signals, particularly those observed at supraphysiologic exposure levels or in non-human models, have frequently led to premature abandonment of otherwise biologically compelling targets
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References Wilding, J
The GSTM1 gene helps your body process glutathione
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