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The critical word here is "forces." Retinoids suppress cell cycle inhibitors and induce proliferation genes regardless of whether the cell is ready to divide
The original concern came from adverse-event reports and observational data that are confounded by the diabetes and obesity these patients already have
Botros, B
Yoon HS, Cho CH, Yun MS, Jang SJ, You HJ, Kim JH, et al
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