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Systemic side effects are rare at low doses, with transient nausea or mild headache reported infrequently
Studies of physical activity in dogs have associated regular exercise with several positive health outcomes, including maintenance of healthy weight and lean body mass, increased energy expenditure, improved glucose metabolism, and strengthening of the human-animal bond
Getting SJ, et al
In autoimmune diseases, mitochondrial dysfunction and impaired mitophagy fuel chronic inflammation by releasing ROS and mtDNA, which activate innate immune pathways and promote autoreactive immune responses
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