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References Crichton ML, Craven NM, Davey R, Horsfall M, Whitehead C, et al

GLP-1 Receptor Agonist Market Insights, By Drug Class: Liraglutide Contributes the Highest Share of the Market Owing to its Effectiveness and Superior Efficacy In terms of drug type, liraglutide is expected to contribute 26.5% share of the market in 2026, as its once-daily subcutaneous administration provides consistent glycemic control throughout the day

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NICE guidance on obesity pharmacotherapy is based on robust, peer-reviewed evidence from completed trial programmes, and retatrutide has not yet reached that threshold

The FDA explicitly warns against using illegally marketed or compounded drugs without proper medical oversight, emphasizing the critical safety advantage of regulated pharmaceuticals over unregulated supplements like berberine