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The authors concluded: The use of GLP-1 agonists should be considered in T1DM patients who are overweight or obese and not at glycemic goals despite aggressive insulin therapy. After conducting clinical trials with a GLP-1 agonist, Novo Nordisk decided not to pursue FDA approval for treating type 1 diabetes

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Published scientific literature has examined FOXO4-DRI (Proxofim) in preclinical research contexts exploring FOXO4-p53 protein-protein interactions and cellular senescence biology