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Most patients have reached their primary treatment objectives by this point
Of note, they did not investigate duration of diabetes or C-peptide levels, which reflects the -cell reserve of each individual
The durability of this response and its relevance for long-term weight maintenance remain to be determined
Current research trajectories indicate accelerated pathways toward regulatory approval and eventual clinical availability
However, the high total-body content of glutathione (probably in the range of 40 to 80 gm in a 70 kg adult) and the relatively short half-life of this reactive and metabolically important compound (4 to 10 hours in most tissues) render glutathione replacement extremely difficult to achieve in practice
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