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Garg concluded by citing a 2024 study, showing off-label prescribing of both GLP-1 RAs and SGLT2 inhibitors in T1D increased significantly between 2010 and 2023, often associated with elevated cardiorenal risk profiles
Additionally, the RCTs testing these drugs for weight loss werent designed to capture these GI events
however, we have lots of drugs that have proven their benefit off-label
Each pen comes pre-filled with the correct amount of the medication that needs to be injected every week
Average weight loss at 72 weeks was 12.8% with 10 mg and 14.7% with 15 mg tirzepatide, compared to 3.2% with placebo
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