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Molecular Aspects of Medicine 28, 538-590

Pineal peptides work best as part of a comprehensive sleep optimization strategy that includes appropriate light exposure (bright in morning, dim in evening), consistent sleep-wake times, cool sleeping environment (65 to 68 degrees Fahrenheit), limited stimulants after noon, and reduced screen exposure before bed

Topical applications are used primarily for skin benefits but may not significantly affect overall glutathione levels

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1b), we favor an attack of roGFP2 at the glutathione sulfur atom as the most likely roGFP2 oxidation pathway (reverse reaction from mechanism (ii) or (iii) from Fig