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But these were different trials, different populations, and different primary endpoints
5 Journal of Orthopaedic ResearchChang CH et al
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In addition, the basal ganglia targeting efficiency and bloodbrain barrier penetration of ferroptosis inhibitors (such as Fer-1) have not been evaluated, and long-term safety data in HD patients are lacking, including whether treatment disturbs iron metabolism in unaffected brain regions and causes cognitive side effects
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