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Notably, primates who were treated at an adipotide dose of 0.43mg/kg daily for four weeks [1]: Exhibited normal levels of activity without any overt clinical signs of nausea, vomiting, or food aversion Showed normal lipid profiles that did not vary throughout the study Registered higher levels of serum creatinine from adipotide doses of 0.25mg/kg Increased urine, with mild dehydration being reported at the highest adipotide dose levels Most changes in the primates serum and urine were reversed within 28 days following discontinuation of treatment [1]

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AOD-9604 completed six human trials enrolling more than 900 participants between the late 1990s and 2007