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BAPTA-AM is activated by intracellular esterases to form BAPTA, which specifically chelates intracellular free Ca, promoting the restoration of calcium homeostasis and inhibiting endoplasmic reticulum stress and calcium-dependent apoptosis pathways

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After invasion of host cells by individual parasites, they undergo many rounds of nuclear doubling within their apical vacuoles to progress from single nuclei (1n) to 2n-, 4n-, and finally 8n-parasites

This regulatory status differs from what happened with tirzepatide compounding