The company said that in its most recent clinical trial, the discontinuation rate due to side effects increased with the dosage, with the highest discontinuation rate, 11.3%, at the highest dosage of 12 mg
However, the Zepbound label for weight management includes a warning to monitor patients for depression, suicidal thoughts, and unusual mood changes
FINAL THOUGHT I love what they are trying to do
The carriers of the loss-of-function GIP receptor variants, R190Q and E288G, display higher blood pressure and an increased tendency toward hypertension (99) but a comprehensive study of larger number of loss-of-function GIP receptor variants did not reveal similar effects on cardiovascular traits (39)
Symptoms such as palpitations, dizziness, or fainting require immediate medical attention