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This was observed even after controlling for weight loss, suggesting a direct joint-protective effect
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Palacka, P., Kucharska, J., Murin, J., Dostalova, K., Okkelova, A., Cizova, M., Waczulikova, I., Moricova, S., and Gvozdjakova, A
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However, in patients with severe renal impairment, a 22% higher mean exposure was observed compared to patients with normal renal function
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