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The FDA requires specific warnings in prescribing information based on animal study findings and theoretical concerns

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242 Most neutrophil chemoattractant receptors are GPCRs that strongly activate neutrophil chemotactic migration

Adults (ages 1855) In a placebo-controlled study with 420 adults, Vyvanse improved ADHD-RS scores significantly more than placebo (effect sizes: 0.73 for 30 mg, 0.89 for 50 mg, 0.99 for 70 mg)