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In the Phase 2 obesity trial it produced about 24% weight loss at 12 mg over 48 weeks, the most of any drug in the class, and it cut liver fat by 86% in the people who started with fatty liver. In the 80-week Phase 3 obesity trial of 2,300 adults with an average BMI of 40, 12 mg produced 28% weight loss and 9 mg reached 26%

(PubMed) Ziegler D, Ametov A, Barinov A, et al

[ CrossRef ] [ Google scholar ] [ PubMed ] Park JR, Lee H, Kim SI, Yang SR

Unlike general supplements or standard issue pharmaceuticals, peptides tend to behave more like precisely targeted messengers, mimicking natural hormones or enzymes in the body