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Real needle-free options exist: the Wegovy oral tablet (FDA-approved December 2025) and experimental microneedle patches in early clinical trials

The percentage of patients diagnosed with thyroid cancer was 0.23% in the DPP4i group, 0.17% in the GLP-1RA group, 0.17% in the SGLT2i group, and 0.20% in the SU group

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BPC-157, short for Body Protection Compound-157, is a synthetic peptide consisting of 15 amino acids derived from a protective protein naturally found in human gastric juice

GLP-1MK-801 also displayed superior weight loss efficacy compared with co-administration of GLP-1 and MK-801, despite having similar effects on food intake (Extended Data Fig