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There are limits set for silymarin in national pharmacopoeias, for example, the British Pharmacopeia (BP) and United States Pharmacopeia (USP) specify a minimum content of 1.5% for silymarin (20)

Am Heart J 1(227):5663 Chioncel O, Lainscak M, Seferovic PM, Anker SD, Crespo-Leiro MG, Harjola VP et al (2017) Epidemiology and one-year outcomes in patients with chronic heart failure and preserved, mid-range and reduced ejection fraction: an analysis of the ESC Heart Failure Long-Term Registry

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