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Importantly, functional B12 deficiency can sometimes coexist with high total B12 levels, especially in kidney disease, and may require additional testing with methylmalonic acid (MMA) or holotranscobalamin if deficiency is suspected clinically

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A medicao administrada por injeo semanal, assim como os demais anlogos de incretina, mas requer escalonamento de dose para reduzir efeitos gastrointestinais e est sendo testada em diferentes doses (9mg e 12mg) no estudo TRIUMPH4