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These figures havent been established in human trials, and long-term human safety data doesnt exist
This difference is likely to be related to the more tightly packed ECD interface of RAMP2 and CTR, driven by the interactions with P37 Cagri , and the preferential CTR engagement by Cagri via a bypass conformation, as discussed below in the context of CTR complexes
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can be part of orthognathic surgery