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The American Diabetes Association (ADA) recommends it as a first-line therapy for type 2 diabetes patients at high risk of cardiovascular disease, and it is already widely prescribed for metabolic dysfunction-associated steatohepatitis (MASH) and chronic kidney disease, as well as blood glucose and obesity management

A few months later, on Today, she dodged questions about a return from Savannah Guthrie, but refused to take the opportunity to say it wasnt happening

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In February 2026, full results from the REDEFINE 2 study showed CagriSema achieving 23% weight loss at 84 weeks but falling short of its primary endpoint under the treatment policy estimand (which measures efficacy across all patients regardless of whether they completed treatment, rather than only those who remained on it)