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Preclinical studies indicate it counteracts toxin-induced liver injury by modulating oxidative stress and inflammation via pathways like Nrf2/HO-1 and NF-B
The pivotal trials by Falutz et al
the EMA and UK SmPC attribute this to weight loss rather than a direct drug effect
Your provider may recommend periodic reassessment of metabolic markers and nutritional status as your weight and metabolic health improve
If over-the-counter products are insufficient, further NHS-available options including iontophoresis and botulinum toxin injections via GP referral or dermatology may be appropriate
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