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They studied 30 workers exposed to lead and a group of 27 unexposed controls
GPX4 Independent Ferroptosis Pathway Although GPX4 is the core molecule of ferroptosis, we have now found other pathways that influence PLOOH synthesis and ferroptosis ( The first is the ferroptosis inhibition protein 1(FSP1) (5860), which can reduce the mevalonate pathway produced ubiquinone translate to ubiquinol, suppress production of PLOOH, and eventually inhibit ferroptosis (58)
2019;179(7):1483-1498.e1422
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van Ophoven, A
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