The downstream effects are dramatic: keratinocyte proliferation and differentiation accelerate, the epidermis compacts and normalizes, melanin transfer is disrupted (fading pigmentation), and dermal fibroblasts are stimulated to produce new collagen while matrix-degrading enzymes (MMPs) are suppressed
However, our bodies do not always produce enough glutathione, especially under stress, poor diet, or aging
Insulin resistance is the hallmark of metabolic syndrome an increasingly common disorder diagnosed by the presence of three of five metabolic abnormalities: high blood pressure, elevated fasting triglycerides, low levels of beneficial HDL cholesterol, increased abdominal circumference, and high fasting blood glucose (Bassi 2014
34 Tobacco and nicotine
Natural ingredients for darker skin types: Growing options for hyperpigmentation