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The majority of the alterations are irreversible and appear in the fourth or fifth decade of life

Before human translation, essential parameters to define: optimal dosing, infusion/administration route, frequency, biomarkers to monitor (senescent cell burden, inflammatory cytokines, organ function), long-term follow-up for adverse outcomes (especially tumour risk)

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Epithalon is primarily recognized for its potential role in the modulation of telomerase activity, a key enzyme involved in the maintenance and elongation of telomeres