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The submission is supported by the SURPASS-CVOT trial, which showed that Mounjaro reduced the risk of MACEincluding CV death, heart attack, or strokeby 8% compared with Trulicity (p=0.086), demonstrating noninferiority to Trulicity regarding CV risk
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Genome-wide association analyses of esophageal squamous cell carcinoma in Chinese identify multiple susceptibility loci and gene-environment interactions
Mutations of the interfacial residues in DET1 to glycine or alanine, including R488A/H485G, R488A/H485G/R306G/S312G or R488A/H485G/E380A/T382A reduced the interaction between DET1 and COP1
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