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Semaglutide creates a significant calorie deficit, often 500 to 1,000 calories below maintenance, and without adequate protein stimulus, the body sacrifices muscle to fill the gap
E.FieldsH
D.et al (2019)
Clinical trials have demonstrated that semaglutide can reduce hemoglobin A1c by approximately 1.0-1.5% in patients with type 2 diabetes (with effects varying by dose and population) and produce weight loss of 10-15% of body weight when used at higher doses for obesity management
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