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Eukaryotic organisms have devised complex metabolic policies that restrict the amount of deuterium reaching the mitochondria, because it damages the ATPase pumps, leading to release of excessive reactive oxygen species and inefficiencies in ATP production

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HyPer7 responses confirmed the cell cycle and metabolic cycle-associated H 2 O 2 cycles that we previously reported, based on roGFP2-Tsa2C R sensor responses 34,35

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