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176 GLP-1RAs and diseases As a rising star in recent years, GLP-1RAs are not only effective in metabolic diseases but also play a role in non-metabolic disorders, affecting multiple systems including the musculoskeletal, nervous, cardiovascular, and digestive systems, and can even have implications in oncological diseases
We conducted a comprehensive literature search across databases, including PubMed and Web of Science, compiling data from clinical trials, case reports, and basic research studies published up to 2025, with a focus on the efficacy, safety, and mechanism of action of drugs such as liraglutide, semaglutide, and tirzepatide in patients with MC4R deficiency
Baseline population: 45 years old on average, 65% female, BMI 39, mean weight 113 kg, 16 years of obesity history
These are direct evidence of GLP-1-mediated gastric emptying delay
How is it possible for compound pharmacies to sell GLP-1 if the drug just came out
US$ 21.63
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