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Notably, after three consecutive days of intraperitoneal administration of leptin, SG-treated rats exhibited a significantly greater suppression of food intake than sham-operated rats, indicating enhanced leptin sensitivity following surgery [96]

Reference: Full article: MedCentral Tirzepatide and Hypogonadism Study link: DOI: 10.1186/s12958-025-01425-9 Tirzepatide Shown to Tackle Hypogonadism from ENDO 2025: CME INDIA Clinical Pearls: Tirzepatide in Obesity-Associated Hypogonadism @Rssdi_official @IndiaESI @AskDrShashank @banshisaboo @DrAmbrishMithal @dramitaol @KapoorNitinDr @DrShubhaSandill @DrKhushboo_Endo @ Key Takeaways: Metabolic hypogonadism in obese men is an underdiagnosed but clinically significant condition, closely linked with insulin resistance and increased diabetes risk

(3) Fielding R, et al

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