For more evidence-based peptide comparisons and the latest on retatrutide's progress, explore the full library at Helpful Tools Related Articles Retatrutide vs Tirzepatide Compared Retatrutide vs tirzepatide compared: 28.7% vs 22.5% weight loss, triple vs dual agonist mechanism, side effects, dosing, cost, and FDA status
Zepbound (tirzepatide) Zepbound is the brand name of tirzepatide the same active ingredient found in Mounjaro
Because retatrutide acts on three receptors, some researchers call it a triple agonist. This design may explain why trial results gained so much attention
This may cause diarrhea, nausea and vomiting
Additionally, some people experience mild side effects such as nausea or a slight upset stomach during the adjustment period