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When name-brand GLP-1s such as Wegovy first started being prescribed for weight loss, in 2021, they were inaccessible for most Americans because of their steep cost and insurance providers limited coverage
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Clinical trials of semaglutide, including the STEP (Semaglutide Treatment Effect in People with obesity) program, have shown that approximately 2540% of total weight lost may come from lean body mass, with the remainder from fat mass
Anecdotally, some patients and practitioners claim positive results, but this is not scientifically proven
If needed, pens may be kept at room temperature (up to 86F or 30C) for up to 21 days
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