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1 Thus, their clinical use is expected to grow rapidly not only because of the obesity epidemic but as evidence expands to other indications such as cardiorenal disorders, metabolic liver disease, obstructive sleep apnea, peripheral vascular disease, depression, addiction, and neurodegenerative diseases
In the trial, 930 adults with type 2 diabetes were randomly assigned to receive weekly retatrutide or placebo
Special population dosing considerations may necessitate modifications to the standard titration schedule
Thats where habit-building comes in
This article summarises the position reached with the GLP-1 RAs and reviews the developing field of unimolecular co-agonists that act not only on the GLP-1 receptor, but on other receptors, notably glucose-dependent insulotropic polypeptide (GIP) and glucagon receptors, with the aim of further improving glycaemic control and weight reduction
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