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doi:10.1016/j.bbrc.2011.08.110 114
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These effects are generally mild and resolve within the first week
Conflict of interest Author GS was employed by eProov Assessment Solution Pvt., Limited
Higher NAD+ activates the sirtuin family of NAD+-dependent deacetylases, particularly SIRT1, which deacetylates PGC-1alpha (promoting mitochondrial biogenesis), FOXO transcription factors (enhancing stress resistance), and NF-kappaB (reducing inflammation)
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