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However, neither of the treatment groups was associated with the reduction in MHD, whereas MHD at baseline was (M3: \(\beta\)= 0.29, 95% CI 0.46, 0.11

In clinical trials, up to 8% of people taking semaglutide reported experiencing headaches

The semaglutide group showed a linear trend towards reduced in-trial MACE risk with increasing weight loss