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The gene showed low activity in stationary macrophages (M0), increases in pro-inflammatory differentiated cells (M1 macrophages), and decreases in cells differentiating into anti-inflammatory macrophages (M2 macrophages) (69)
This is the simplest solution when the timing works
Induced pluripotent stem cell-derived MSCs (iPSC-MSCs) activate CD4+ and CD8 + T cells, upregulate and activate Treg cells, and balance Th1/Th2 cytokine levels without any additional stimulation [147]
Residual activity was compared to controls incubated with equal volumes of inhibitor solvent
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