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The study included two cohorts: 40 women using menopause hormone therapy concurrently with tirzepatide and 80 women using tirzepatide alone
Constipation is manageable through hydration, fiber, laxatives, and physical activity
Patients losing 12 pounds per week on lifestyle intervention alone typically don't report significant facial hollowing because subcutaneous fat depletion occurs slowly enough for dermal remodeling to keep pace
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