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However, the heterogeneity of CKD may obscure disease-specific drug effects, underrepresent Alport patients, and delay the discovery of targeted therapies

Hospital systems were comparably affected, for example, UPMC out of Pittsburgh posted an even larger loss of about $370 million over the same term, which it attributed to increased medical utilization and pharmacy costs, while Highmark Health - also of Pittsburgh - despite avoiding operational losses, reported a significant decline in operating gains in 2024 relative to 2023, which administrators blame on high prescription drug costs - most notably GLP-1s

M., Machineni, S., et al

United States and Australian regulators have recently approved Wegovy for that purpose, although it hasnt been available for use in Australia to date

Multidimensional tracking of GPCR signaling via peroxidase-catalyzed proximity labeling