However, there has been no scientific approach that aims to balance the DSIP level to date
Maybe you do not
You fight the resistance, the plunger keeps pulling back, and you end up with an inconsistent draw that may include air and less medication than you intended
Finer gauges (a higher number means a thinner needle 32G is finer than 29G) hurt less and bruise less, but they also flow more slowly, which matters when you are drawing a thicker liquid from a vial
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