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In this narrative review we introduce the preclinical data related to this receptor pathway and pancreatic ductal adenocarcinoma

An in vitro study was conducted using pancreatic -cell line, MIN-6, stably expressing GLP-1R (GLP-1R-MIN-6 cells) and intestinal L-cell line, GLUTag

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Research published in Nutrients (2023) and updated clinical reviews in early 2025 demonstrate that these SCFAs act as chemical keys that unlock the L-cells in your colon, directly triggering the release of GLP-1 into your bloodstream