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Three B vitamins are therefore essential for keeping homocysteine levels in check: Vitamin B12 (in the methionine synthase pathway) Folate (B9) (also in the methionine synthase pathway) Vitamin B6 (in the cystathionine beta-synthase pathway) When any of these three is low, the body cannot process homocysteine efficiently, and blood levels rise
In preclinical tests, the most commonly noted side effect was mild local irritation at the injection site
Implications for paracrine and target-derived Neurotrophic functions
Between 15-40% of people over 60 have low serum B12 levels (Pacholok & Stuart, 2011)
