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[10] PA may be suspected when a patient's blood smear shows large, fragile, immature erythrocytes, known as megaloblasts

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La enzima dipeptidil peptidasa-4 (DPP-4) y, en menor medida, la endopeptidasa neutra degradan rpidamente el GLP-1 circulante, lo que limita su duracin de accin y representa un desafo para su uso teraputico directo

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Importantly, vascular endothelium is known to play an important role in the maintenance of cardiovascular function 10