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For research designed to replicate or build on the existing literature, the 1:1 ratio is the proportion that connects your work to the existing evidence base
J Neurol Neurosurg Psychiatry 90:507513 Collatz A, Johnston SC, Staines DR, Marshall-Gradisnik SM (2016) A systematic review of drug therapies for chronic fatigue syndrome/myalgic encephalomyelitis
Biochim Biophys Acta 1969
However, researchers estimate that the lethal dose of GHK-Cu would be about 330 mg/kg of body weight, which is over 300 times larger than its known effective dose
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