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Mitochondrial Protection (The Shield): High-intensity aerobic exercise generates a massive influx of reactive oxygen species (ROS) that damage cellular machinery
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Accordingly, people with type 2 diabetes, cardiovascular disease, heart failure, or chronic kidney disease should be treated appropriately with an SGLT-2 inhibitor or GLP-1RA, even because more adults with type 2 diabetes in the US have suboptimal glycemic control now compared to 10 years ago, associated with a resurgence in vascular diabetic complications [32]
Inform patients that if symptoms of thrombocytopenia occur, stop taking BYETTA and seek medical advice promptly [see Warnings and Precautions (5.8)]
Tirzepatide versus insulin degludec in patients with type 2 diabetes (SURPASS3): A randomized, openlabel trial
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