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To determine whether GLP-1R overexpression mediates ASM cell inflammatory cytokine release, the levels of IL-6, IL-8, TNF- and GM-CSF were measured
In contrast, protective metabolites [e.g., short-chain fatty acids (SCFAs), bile acid (BA), hydrogen sulfide (HS), and indole derivatives] offer compensatory protection through opposing pathways, including anti-inflammatory effects, antioxidant activity, and maintenance of metabolic homeostasis
Kim M, Platt MJ, Shibasaki T, Quaggin SE, Backx PH, Seino S, et al
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