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What we do know: -Strong preclinical evidence suggests GLP-1RAs reduce drug/alcohol intake, motivation, and relapse

This reduction in appetite can result in decreased food intake, which contributes to overall calorie reduction and, consequently, weight loss

Side effects and overall treatment experience vary by individual

Heat, sweat, and busy schedules can throw off your fluid and electrolyte balance fast, and thats often the real reason behind that mid-afternoon slump

Future clinical studies should determine which patient groups should be targeted as potential candidates for the symptomatic and/or neuroprotective effects of GLP-1RAs, to find out, whether combinations of GLP-1RA with other classes of drugs can further enhance their effectiveness, and evaluate their long-term effect on the course of the disease and side effects