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Hypokalemia and thrombocytosis could occur upon conversion of severe megaloblastic anemia to normal erythropoiesis with methylcobalamin therapy

Consistent with previous evidence that butyrate suppresses microglial inflammatory activation [41], we observed a strong inverse association between butyrate levels and indices of microglial lipotoxicity, highlighting butyrate as a potential therapeutic target in biodegradable MP-associated neurotoxicity

10.1016/j.chembiol.2008.02.010 Chem

Saccon, R

Oxidative stress in the CNS acts as a persistent inflammatory trigger by activating brain-resident immune cells, particularly microglia and astrocytes